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Modified oligonucleotides comprising these backbone analogues, despite having different backbone sugars or using amino acid residues instead of ribose phosphate in the case of PNA, bind to RNA or DNA according to Watson and Crick pairing (Watson and Crick pairing) and are immunogenic to nuclease activity

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Nonetheless, its evident and strong relationship with tellurium prompted the scientist to choose its name: “However, to recall the relationship of the latter with tellurium, I named it selenium .” [1] In 1819, the first publication in a scientific journal on selenium appeared in the Swedish Afhandlingar i Fysik, Kemi och Mineralogi (Theses in Physics, Chemistry and Mineralogy) and the history of selenium began, [1] a history which is still far from being complete